Niacinamide Serum Comparison: Zinc, Vitamin C+E, Rice Water and More

Niacinamide serums differ less by concentration than by what the niacinamide is paired with. Four of the five serums use a niacinamide base near 10%. Dot & Key uses a lower 5% concentration.

Niacinamide is a form of vitamin B3 that supports the skin barrier and helps regulate sebum production. It’s also linked to more even-looking skin tone. For more on how niacinamide works, see how niacinamide works.

Review counts below reflect purchase and review volume, not fit or quality.

We don’t show a price here because it wasn’t checked in the last 24 hours — the listing may have changed. Price last checked 2026-09-10 for all five listings.

All five serums are sold on Nykaa.

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• Dot & Key 10% Vitamin C + E Face Serum With 5% Niacinamide — Dot & Key’s serum pairs Vitamin C and Vitamin E with a lower 5% concentration of niacinamide. Vitamin C and Vitamin E are antioxidants often used together. Vitamin E helps stabilize Vitamin C in these formulas. It has 62,814 reviews.
• Minimalist 10% Niacinamide Face Serum With Matmarine + Zinc — Minimalist combines 10% niacinamide and zinc with Matmarine, a branded marine-derived ingredient. Matmarine doesn’t have an established mechanism the way niacinamide and zinc do. It has 134,772 reviews.
• Plum 10% Niacinamide Brightening Face Serum with Rice Water — Plum builds its 10% niacinamide serum around rice water and markets it for brightening. Rice water contains starches, amino acids, and antioxidants. It’s traditionally used for soothing and brightening in skincare. It has 144,181 reviews.
• The Derma Co 10% Niacinamide Face Serum For Acne Marks — The Derma Co markets its 10% niacinamide serum specifically for acne marks. It has 74,640 reviews.
• The Ordinary Niacinamide 10% + Zinc 1% — The Ordinary lists just niacinamide 10% and zinc 1%, with no other active named in the title. Zinc is often paired with niacinamide for oil control and soothing. It has 167,892 reviews, the highest of the five here.

If antioxidants are the priority, pick Dot & Key. If you want zinc alongside an added marine-derived ingredient, pick Minimalist. If brightening with rice water appeals to you, pick Plum. If acne marks are your concern, pick The Derma Co. If you want the simplest niacinamide-and-zinc formula, pick The Ordinary.

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